View Full Version : Recent Articles on Finnish DNA - Links

23-09-06, 06:18
These may or may not be helpful.

The first four articles are specifically Finnish. The remainder are comparative studies of European DNA (mostly mtDNA).

Note: these are technical articles, which are pretty "hard sledding" for anyone without some background in molecular biology.

The first article has maps, which can be compared to known historical migration patterns in Finland.

Note that Finnish males (Y) have a different pattern than Finnish women (mt).

For a less technical article (which includes practical genetics and genealogy), see "Finland’s Fascinating Genes"


Discussion is invited.


M. Hedman, V. Pimenoff, M. Lukka, P. Sistonen, A. Sajantila (2004)
Analysis of 16 Y STR loci in the Finnish population reveals a local reduction in the diversity of male lineages
Forensic Science International 142 (2004) 37-43

PDF version: www.familytreedna.com/pdf/Finnish.pdf

Saara Finnilä, Ilmo E. Hassinen, Leena Ala-Kokko, and Kari Majamaa (2000)
Phylogenetic Network of the mtDNA Haplogroup U in Northern Finland Based on Sequence Analysis of the Complete Coding Region by Conformation-Sensitive Gel Electrophoresis
Am. J. Hum. Genet. 66:1017-1026

HTML version: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1288139
PDF version: http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1288139&blobtype=pdf

Finnilä, Saara (2000)
Phylogenetic analysis of mitochondrial DNA Detection of mutations in patients with occipital stroke. Available online at Oulu University Library

HTML version: http://herkules.oulu.fi/isbn9514255674
PDF version: http://herkules.oulu.fi/isbn9514255674/isbn9514255674.pdf

Kristiina Tambets, and others (2004)
The Western and Eastern Roots of the Saami-the Story of Genetic
“Outliers” Told by Mitochondrial DNA and Y Chromosomes
Am. J. Hum. Genet. 74:661-682

PDF version: www.oxfordancestors.com/papers/mtDNA04%20Saami.pdf

Finnilä S, Lehtonen MS, Majamaa K. (2001)
Phylogenetic network for European mtDNA.
Am J Hum Genet. 2001 Jun;68(6):1315-20.

PDF version: http://www.journals.uchicago.edu/AJHG/journal/issues/v68n6/002593/002593.web.pdf

A. Torroni, K. Huoponen, P. Francalacci, M. Petrozzi, L. Morelli, R. Scozzari, D. Obinu, M. L. Savontaus and D. C. Wallace (1996)
Classification of European mtDNAs From an Analysis of Three European Populations
Genetics, Vol 144, 1835-1850

PDF version: http://www.genetics.org/cgi/reprint/144/4/1835.pdf

Martin Richards, Vincent Macaulay, Antonio Torroni, and Hans-Jürgen Bandelt (2002)
In Search of Geographical Patterns in European Mitochondrial DNA
Am J Hum Genet. November 2002; 71(5): 1168-1174.

PDF version: http://www.pubmedcentral.org/picrender.fcgi?artid=385092&blobtype=pdf

Malyarchuk BA, Grzybowski T, Derenko MV, Czarny J, Wozniak M, Miscicka-Sliwka D. (2002)
Mitochondrial DNA variability in Poles and Russians.
Ann Hum Genet. 2002 Jul;66(Pt 4):261-83.

PDF version: www.familytreedna.com/pdf/MALYARCHUK.pdf

24-09-06, 03:20
(continuation of prior post)

Here is a good general site for DNA studies in the context of human migration patterns.

"Genetic Chaos" ("About - Using genetic research to study human migration patterns.") Despite its title, it is far from chaotic.


It has an adequate serach engine and abstracts of articles for each month. Most articles can be accessed directly from the abstracts or search.

In the post above, I noted that Finnish mtDNA has a different pattern from Finnish Y DNA. Here is the summary of Tuuli Lappalainen's 2006 article on that. The upshot is that Finnish Y is a bit complex - one cannot draw broad conclusions from isolated data.

"The aim of this study was to gather genetic evidence of the substructure of the Finnish population, to evaluate with a more detailed sample material the theory of a dual origin for the Finns earlier supported by the genetic findings of Kittles et al. (1998), and to further elucidate the contribution of European, Finno-Ugric or other founders by using a set of phylogenetically informative markers. To achieve this aim, we analyzed Y chromosomal variation of 536 unrelated men from 9 provinces of Finland with 14 biallelic markers and 8 STRs.

"Classical studies with blood group antigen markers such as ABO, Rh+/− and MN in Finns have shown large differences in frequencies at the county level, but not at the level of whole regions of the country (Mustakallio, 1989; Nevanlinna, 1973; Workman et al., 1976). Studies with maternally inherited mtDNA have drawn a picture of high homogeneity in the regional variation of the Finnish population, together with a clear European pattern (Finnila et al., 2001; Sajantila et al., 1995; Vilkki et al., 1988).

"In contrast, patrilineal markers of the Y chromosome have propounded both reduced variation and an east–west frequency gradient (Hedman et al., 2004; Kittles et al., 1998, 1999a,b; Raitio et al., 2001). In the present study, we found further support for the proposed sharp distinction between the eastern and western male subpopulation groups in Finland (Kittles et al., 1998), together with some local differences within the two geographical groups. Furthermore, our analysis of the phylogenetically informative biallelic markers revealed interesting features about the Finnish population history."

The URL is below.

Tuuli Lappalainen and others (2006)
Regional differences among the Finns: A Y-chromosomal perspective
Gene, Volume 376, Issue 2 , 19 July 2006, Pages 207-215

PDF version: http://vetinari.sitesled.com/finns.pdf


02-10-06, 19:20
I recently had my Y-DNA tested using 44 markers. I would be happy to participate in any research or programs that would shed further light on Finnish Genealogy.I read with interest two of the posted articles and was able to match my markers against those in the 31.7.2003 research article.